| Organisation of 75th edition | |
| Category | ME (Men Elite) |
| Class | 1.1 (Europe Tour) |
| Organiser | - |
| Director | - |
| Timer | - |
Route |
| 27 June 2021 (Sunday) | ||
| Profile |  |
One-day race |
| Start |  |
Lugano |
| Finish | |
Lugano |
| Distance | 184.0 km (114.3 mi) | |
| Speed | 37.679 km/h (23.413 mi/h) | |
Results (Top 10) |
| # |  |
Rider | Age | Team | Time | Gap | ||
| 1 | 35 |  |
Moscon, Gianni | 27 |  |
Ineos Grenadiers | 4h 53' 00'' | |
| 2 | 5 | |
Conti, Valério | 28 |  |
UAE Team Emirates | 4h 53' 20'' | + 00' 20'' |
| 3 | 23 |  |
Hermans, Ben | 35 |  |
Israel Start-Up Nation | 4h 53' 20'' | + 00' 20'' |
| 4 | 65 | |
Pellaud, Simon | 28 | |
Androni Giocattoli - Sid.. | 4h 53' 32'' | + 00' 32'' |
| 5 | 1 | |
Ulissi, Diego | 31 | |
UAE Team Emirates | 4h 53' 56'' | + 00' 56'' |
| 6 | 97 | |
Velasco, Simone | 25 |  |
Gazprom - RusVelo | 4h 53' 57'' | + 00' 57'' |
| 7 | 45 |  |
Smith, Dion | 28 |  |
Team BikeExchange | 4h 54' 27'' | + 01' 27'' |
| 8 | 112 | |
Orrico, Davide | 31 | |
Vini Zabù KTM | 4h 54' 27'' | + 01' 27'' |
| 9 | 162 | |
Tizza, Marco | 29 |  |
Amore e Vita | 4h 54' 28'' | + 01' 28'' |
| 10 | 175 |  |
Wildauer, Markus | 23 | |
Team Vorarlberg | 4h 54' 33'' | + 01' 33'' |