| Organisation of 105th edition | |
| Category | ME (Men Elite) |
| Class | 1.UWT (World Tour) |
| Organiser | - |
| Director | - |
| Timer | - |
Route |
| 4 April 2021 (Sunday) | ||
| Profile |  |
One-day race |
| Start |  |
Antwerpen |
| Finish | |
Oudenaarde |
| Distance | 254.0 km (157.8 mi) | |
| Speed | 42.076 km/h (26.145 mi/h) | |
Results (Top 10) |
| # |  |
Rider | Age | Team | Time | Gap | ||
| 1 | 12 |  |
Asgreen, Kasper | 26 | |
Deceuninck - Quick-Step | 6h 02' 12'' | |
| 2 | 1 |  |
Poel, Mathieu van der | 26 | |
Alpecin - Fenix | 6h 02' 12'' | + 00' 00'' |
| 3 | 21 | |
Van Avermaet, Greg | 35 |  |
Ag2r Citroën Team | 6h 02' 44'' | + 00' 32'' |
| 4 | 51 | |
Stuyven, Jasper | 28 |  |
Trek - Segafredo | 6h 02' 45'' | + 00' 33'' |
| 5 | 81 | |
Vanmarcke, Sep | 32 |  |
Israel Start-Up Nation | 6h 02' 59'' | + 00' 47'' |
| 6 | 31 | |
Aert, Wout van | 26 | |
Jumbo - Visma | 6h 02' 59'' | + 00' 47'' |
| 7 | 6 | |
Vermeersch, Gianni | 28 | |
Alpecin - Fenix | 6h 02' 59'' | + 00' 47'' |
| 8 | 246 | |
Turgis, Anthony | 26 | |
Total Direct Energie | 6h 02' 59'' | + 00' 47'' |
| 9 | 15 | |
Sénéchal, Florian | 27 | |
Deceuninck - Quick-Step | 6h 02' 59'' | + 00' 47'' |
| 10 | 177 | |
Baarle, Dylan van | 28 |  |
Ineos Grenadiers | 6h 02' 59'' | + 00' 47'' |